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Filtered Search Results
Medchemexpress LLC AR-R17779 hydrochloride | 178419-42-6 | 99.0% | C9H15ClN2O2 | 10MG
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AR-R17779 hydrochloride is a research-grade, potent and selective full agonist of the α7 subtype of neuronal nicotinic acetylcholine receptors, provided as the hydrochloride salt for preclinical pharmacology studies. It is intended for in vitro and in vivo research to probe receptor signaling, cognitive effects, and neuroprotective mechanisms.
- Potent, selective α7 nicotinic acetylcholine receptor agonist.
- High purity (99.0%) suitable for research applications.
- Supplied as a white to off-white solid for ease of handling.
- Stable under recommended storage conditions to preserve activity.
- Suitable for in vitro assays and in vivo pharmacology studies.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules Chem-Impex Ninhydrin 5kg 288406338 00462 0 000 485-47-2 MFCD00003791 178 143 C9H6O4
Chem-Impex Ninhydrin 5kg 288406338 00462 0 000 485-47-2 MFCD00003791 178 143 C9H6O4
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Medchemexpress LLC Calhex 231 hydrochloride | 2387505-78-2 | 99.8% | 443.41 g·mol⁻¹ | C25H28Cl2N2O | 1 ML
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Calhex 231 hydrochloride is a research reagent that acts as a negative allosteric modulator of the calcium-sensing receptor (CaSR). It inhibits CaSR-mediated signaling (reported IC50 ≈ 0.39 μM) and is supplied in multiple formats including a ready-to-use 10 mM solution in DMSO for convenient dosing in cell-based and biochemical assays.
- Negative allosteric modulator of CaSR for research applications.
- Reported activity: IC50 ≈ 0.39 μM against CaSR-mediated responses.
- Available as solid and as a pre-made 10 mM solution in DMSO (1 mL) for easy use.
- High reported purity suitable for experimental use (reported 99.81%).
- Provided with analytical documentation and safety data for laboratory compliance.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Bevantolol hydrochloride | 42864-78-8 | 99.0% | 1 ML
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Bevantolol hydrochloride is a selective β1 and α1-adrenergic receptor antagonist supplied as the hydrochloride salt for research and analytical use. It is commonly used as a reference standard in pharmacology and receptor-binding studies.
- Selective β1 and α1-adrenergic receptor antagonist
- Supplied as the hydrochloride salt suitable for analytical use
- Molecular weight 381.89 g/mol
- Chemical formula C20H28ClNO4
- Typical purity around 98.98% as reported by the manufacturer
- Available as solid reference standards; solution formulations may be offered by suppliers
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Defactinib hydrochloride | 1073160-26-5 | 99.4% | 100 MG
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Defactinib hydrochloride is the hydrochloride salt of defactinib, a small-molecule focal adhesion kinase (FAK) inhibitor that reduces FAK phosphorylation at Tyr397 in a time- and dose-dependent manner. It is used in preclinical research to study FAK signaling, cancer cell migration, and related pathways.
- Small-molecule FAK inhibitor reducing phosphorylation at Tyr397.
- Used for preclinical studies of cancer cell migration and signaling.
- High purity suitable for biochemical and cellular assays.
- Solid form, typically supplied as a 100 mg package.
- Store sealed at 4°C; in solution store at -80°C for long-term storage.
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Medchemexpress LLC Fingolimod hydrochloride | 162359-56-0 | 99.9% | 200 MG
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Fingolimod hydrochloride is the hydrochloride salt of fingolimod (FTY720), a sphingosine 1-phosphate (S1P) receptor modulator supplied for research and analytical applications. It is provided as a high-purity solid with supporting documentation available.
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Medchemexpress LLC GB111-NH2 hydrochloride | 99.3% | 610.14 g·mol⁻1 | C33H40ClN3O6 | 5 MG
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GB111-NH2 hydrochloride is a research-grade small-molecule cysteine cathepsin inhibitor used in biochemical and cellular studies, notably in cancer research.
- High reported purity, 99.3%.
- Molecular formula C33H40ClN3O6; molar mass 610.14 g·mol⁻1.
- Physical form: solid, white to off-white.
- Intended for biochemical and cellular studies related to cathepsin activity and cancer research.
- Available in milligram-scale packages suitable for screening and mechanistic experiments.
- Store sealed, away from moisture and light; in solvent store at -80°C for six months or -20°C for one month.
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Medchemexpress LLC Pholedrine (hydrochloride) | 877-86-1 | 99.6% | 5 MG
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Pholedrine (hydrochloride) is an indirectly acting sympathomimetic amine used as a diagnostic mydriatic and for cardiovascular and adrenergic research. It is supplied as the hydrochloride salt suitable for topical ophthalmic diagnostic use and laboratory studies.
- Used as a diagnostic topical eye drop for Horner's syndrome
- Acts as an indirectly acting sympathomimetic amine
- Reported high purity suitable for research applications
- Hydrochloride salt form for improved handling and formulation
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Medchemexpress LLC Ravidasvir hydrochloride | 1303533-81-4 | 99.9% | 835.82 g/mol | C42H52Cl2N8O6 | 25MG
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Ravidasvir hydrochloride is a research-grade hepatitis C virus NS5A inhibitor used in preclinical and biochemical studies. It is supplied as a white to off-white solid and is available in solid and solution pack sizes. The product has a reported high purity (~99.9%), molecular formula C42H52Cl2N8O6, and molecular weight 835.82 g/mol. Storage recommendations include sealed storage at 4°C and long-term storage in solvent at -80°C.
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Medchemexpress LLC Vimirogant hydrochloride | 1802678-42-7 | 98.4% | C27H35F3N4O3S·XHCl | 10 MG
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Potent, selective RORγt inhibitor supplied as the hydrochloride salt for research use. It demonstrates low-nanomolar biochemical potency and cellular activity against IL-17A secretion and Th17 differentiation.
- Potent RORγt inhibition (Ki = 3.5 nM; IC50 = 17 nM).
- Reduces IL-17A secretion in human PBMCs (IC50 = 18 nM) and human whole blood (IC50 = 192 nM).
- Inhibits Th17 differentiation in mouse splenocytes (IC50 = 57 nM).
- High purity (98.4% by HPLC).
- Available in small research pack sizes, e.g., 10 MG.
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Medchemexpress LLC CZC-54252 (hydrochloride) | 1784253-05-9 | 98.4% | 25 MG
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CZC-54252 hydrochloride is a potent and selective LRRK2 inhibitor. It attenuates G2019S LRRK2-induced human neuronal injury and exhibits neuroprotective activity. This product is a solid, typically light yellow to orange in appearance.
- Potent and selective LRRK2 inhibitor
- Attenuates G2019S LRRK2-induced human neuronal injury
- Exhibits neuroprotective activity
- Molecular weight: 541.45
- Formula: C22H26Cl2N6O4S
- Appearance: Solid, light yellow to orange
- Stable under recommended storage conditions
- Soluble in DMSO
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Medchemexpress LLC SB-743921 hydrochloride | 940929-33-9 | 99.8% | 553.52 | 10 MG
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SB-743921 hydrochloride is a potent inhibitor of the mitotic kinesin KSP (Eg5), with a Ki of 0.1 nM.
- Potently inhibits colony-forming cell (CFC) formation of chronic myeloid leukemia (CML) primary cells.
- Exhibits slight inhibitory activities on the colony-forming ability of normal bone marrow progenitors.
- Induces apoptosis of CML primary CD34+ cells, with slight effect on normal CD34+ cells.
- Displays additive anti-proliferative effect in KCL22 and CML CD34+ cells when combined with imatinib.
- Overcomes imatinib resistance in CML cells.
- Inhibits MEK/ERK and AKT signaling in CML cells.
- Has good oral bioavailability and pharmacokinetics.
- Induces complete tumor regression in nude mice bearing lung cancer patient xenografts.
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Medchemexpress LLC Verapamil hydrochloride | 152-11-4 | 491.06 | 500 MG
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Verapamil hydrochloride is a calcium channel blocker and a potent, orally active first-generation P-glycoprotein (P-gp) inhibitor. It also inhibits CYP3A4 and is used in research for high blood pressure, heart arrhythmias, and angina.
- Acts as a calcium channel blocker
- Functions as a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor
- Inhibits CYP3A4
- Useful for research into high blood pressure
- Used in heart arrhythmias research
- Applied in angina research
- Useful for the prophylaxis of atrioventricular reentry tachycardia
- Modulates the atrioventricular nodal response in atrial fibrillation
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Medchemexpress LLC Enerisant hydrochloride | 1152749-07-9 | 98.7% | 434.96 | 5 MG
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Enerisant hydrochloride | 1152749-07-9 | 98.7% | 434.96 | 5 MG
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Medchemexpress LLC Bobcat339 hydrochloride | 2436747-44-1 | 99.6% | 334.20 | 50 MG
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Bobcat339 hydrochloride is a potent and selective cytosine-based inhibitor of the TET enzyme, with IC50s of 33 μM and 73 μM for TET1 and TET2, respectively. It is useful in epigenetics and serves as a starting point for new therapeutics targeting DNA methylation and gene transcription.
- Potent and selective cytosine-based inhibitor of TET enzyme.
- Useful in epigenetics.
- Serves as a starting point for new therapeutics that target DNA methylation and gene transcription.
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